| CAS No.: | 480-16-0 |
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| Formula: | C15h10o7 |
| EINECS: | 207-542-9 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Samples: |
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| Customization: |
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Chemical Name: Morin
CAS No.: 480-16-0
Chemical Structure: C15H10O7
Molecular weight: 302.24
Appearance: Yellow powder
Assay: 98%min
Morin is a light yellow pigment extracted from the bark of Fustic , such as Fustic and many Chinese herbal medicines.The structure is characterized by an oxygen-containing heterocyclic ring connecting two aromatic rings.It is usually yellow or grayish yellow acicular crystal, easily oxidized to brown in the air for a long time, melting point 285ºC ~ 290ºC (decomposition), slightly soluble in water.Morin is a colorant commonly used in chemical analysis. It is generally used to detect trace amounts of iron, zinc, cobalt, etc. It can also inhibit enzyme activity, and has the functions of anti-oxidation, anti-pain, anti-bacterial , anti-inflammatory, anti-atherosclerosis, reducing blood sugar and anti-stress.
Function
1. Anticancer effect The anti-tumor effects of flavonoids are mainly achieved by inducing tumor cell apoptosis, promoting anti-tumor cell proliferation, interfering tumor cell signal transduction, promoting the expression of pain-suppressing genes, promoting tumor necrosis factor, inhibiting oncogenic agents and anti-oxidation, etc.The results show that the effective point of morin is the carbonyl group of the central three carbon chain and its oxygen atom.Through mulberry pigment anti - free radical effect, direct inhibition of cancer cell growth, anti - carcinogenic pour, inhibit blood vessel growth, improve the body immunity and achieve.Cytoblast (SRFC) number, the decrease of SiC induced by cyclophosphamide, enhanced the proliferation of lymphocytes activated by ConA.
2. Anti-inflammatory immunity The anti-inflammatory mechanism of biological flavonoids may be that they inhibit lipoxygenase (LOX) -J, protein kinase C(PKC), phosphodiesterase, phosphatesterase, lipoxygenase, and cyclooxygenase in the process of prostaglandin (PG) biosynthesis, and can regulate the activity of endothelial cells and inflammatory cells in the inflammatory response.The inhibitory effects of morin on immunity and inflammation are related to its inhibitory activities against these enzymes. Morin plays an anti - inflammatory and immune role mainly through its influence on cell secretion, mitosis and cell interaction.
3. Antioxidant effect There are a lot of free radical scavenging and inhibiting free radical substances in human organism, they macho to remove excess free radicals, prevent lipid peroxidation, so that the generation and elimination of free radicals in the body to maintain a relative balance.However, when the endogenous antioxidant system malfunctions or the body is in some pathological or harsh physiological environment, oxygen free replication will be produced in large quantities at the wrong time and place, and its metabolism will be unbalanced, leading to cell damage, disease and aging.The free radical scavenging mechanism of morin is that, as a metal ion chelator, it blocks the generation of free radicals in the Fenton system, that is, it blocks the decomposition of H202 under the catalytic action of Fe20 to produce · OH.In addition to scavenging free radicals directly, morin can also affect its configuration and conformation by binding with some oxidases in the body, and inhibit the activity of enzymes, thus inhibiting the generation of free radicals.
Application
Applied in agriculture field, matrine can kill the pests.Matrine is a natural plant-based pesticides, low toxicity for human and livestock, which is a broad spectrum insecticide with tag and stomach poison. It has a obvious control treatment effect on all kinds of crops NianChong, caterpillar, aphids, starscream.
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