| Customization: | Available |
|---|---|
| CAS No.: | 459789-99-2 |
| Formula: | C26h44o4 |
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About product
Chemical Name: Obeticholic Acid
CAS No.: 459789-99-2
Chemical Structure: C26H44O4
Molecular weight: 420.63
Appearance: White powder
Assay: 98%min
Obecholic acid is the first drug developed for the treatment of cholestatic liver disease in 20 years. It is aimed at patients with insufficient response or intolerance to ursodeoxycholic acid.
Function
Ins ulin resistance plays an important role in the pathogenesis of NAFLD / NASH. Insu lin sensitizers such as thiazolidinediones have been proved to be effective in improving liver inflammation and fat content, but they can not block the progression of fibrosis caused by Nash. Farneside derivative X receptor also improves in sulin resistance and plays an important role in the metabolism of bile acids, lipids and sugars. OBE chemicalbook cholic acid is a human bile acid simulant. It is a semi synthetic chenodeoxycholic acid. It is also a specific agonist of farneside derivative X receptor. Intercept pharmaceutical company has developed it for the treatment of primary biliary cirrhosis PBC, nonalcoholic steatohepatitis and other liver and intestinal diseases. Animal experiments have proved its role in improving insu lin resistance and reducing liver fat content.
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