| Customization: | Available |
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| CAS No.: | 7689-03-4 |
| Formula: | C20h16n2o4 |
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About product
Chemical Name: (+)-Camptothecin
CAS No.: 7689-03-4
Chemical Structure: C20H16N2O4
Molecular weight: 348.35
Appearance: Yellow powder
Assay: 98%min
Camptothecin is a plant anticancer drug, extracted from Camptotheca acuminata distributed in central and southwestern China. Camptothecin has a good effect on gastrointestinal and head and neck cancer, but it has side effects of hematuria in a few patients. The anti-cancer activity of 10-hydroxycamptothecin is higher than that of camptothecin. It also has obvious curative effect on liver cancer and head and neck cancer, and has fewer side effects.
Camptothecin was originally isolated from the stems of Camptotheca acuminata and showed anti-leukemia and anti-tumor activities.
Camptothecin derivatives mainly include Topotecan (Topotecan, TPT) and Irinotecan Hydrochloride (Irinotecan, CPT-1).
Function
1. Anti tumor effect.
2. Camptothecin can inhibit the proliferation of fibroblasts both in vivo and in vitro.
3. In addition, camptothecin has obvious inhibitory effect on herpesvirus.
4. In vivo, camptothecin is mainly excreted from bile and urine.
5. Camptothecin can induce chromosome aberration and is toxic.
6. Treatment of esophageal cancer, cardiac cancer.
7. Treatment of gastric cancer.
8. Treatment of primary liver cancer.
9. Treatment of psoriasis.
10. Treatment of skin warts.
Application
1. Applied in the functional food field;
2. Applied in the health product field;
3. Applied in the pharmaceutical field.
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