| CAS No.: | 518-34-3 |
|---|---|
| Formula: | C38h42n2o6 |
| EINECS: | 683-095-7 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Samples: |
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| Customization: |
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Chemical Name: D-Tetrandrine
CAS No.: 518-34-3
MF: C38H42N2O6
MW: 622.75
Appearance: White powder
Assay: 98%min
Tetrandrine, also known as tetrandrine and tetrandrine, is a white solid chemical. The chemical name is (S,S)-(+)-tetrandrine;molecular formula is C38H42N2O6, molecular weight is 622.75000, melting point is 217~218ºC, almost insoluble in water, petrol eum ether, soluble in ether, etc. Tetrandrine is an antihypertensive drug, which is mainly used clinically to treat mild and moderate hypertension, and can also be used for hypertensive crisis.
Function
1. Immune system diseases tetrandrine can significantly inhibit the development of arthritis and is stronger than aspirin, and can be applied to the treatment of rheumatoid arthritis.
2. Cardiovascular diseases Hanfang has not only calcium antagonism, but also inhibits T-type and L-type calcium channels in ventricular myocytes, and interacts with M receptors to block calcium-activated potassium channels and become therapeutic arrays. A treatment for supraventricular tachycardia.
3. Digestive system Tetrandrine plays a role in protecting liver cells and anti-fibrosis.
4. Ophthalmic diseases Tetrandrine is used in the treatment of ocular inflammation, including uveitis, keratitis and retinopathy caused by it.
5. Other tetrandrine has obvious antagonistic effect on acute nephrotoxicity induced by streptomycin, can reduce apoptosis and proliferation of renal tubular epithelial cells, protect kidney function, and protect against acute ischemia-reperfusion kidney injury. The effect can significantly reduce serum creatinine and urea nitrogen levels, improve glomerular filtration rate and renal plasma flow, and delay the development of glomerular sclerosis.
Application
1. Applied in agriculture field as raw material, matrine can kill the pests.
2. Applied in pharmaceutical feild as raw materials, matrine is used for anti-bacteria, anti-inflammatory and anti-tumors.
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